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1 绎 圆员 PubMed RCT 24 h 973 RCT RCT SCI doi: /wst R246 A 逸 140 mmhg 逸 90 mmhg 10 1/3 [1] [7] Science Citation Index SCI SCI [8] SCI Randomized Con 原 trol Trails, RCT [2] [3,4] [2] [5] [6] PubMed Web of Science PubMed (acupuncture) AND hypertension (acupuncture) AND blood pressure(acupuncture) AND arterial pressurefull text available Randomized Controlled TrailClinical Trail 元 CB 元元 973 1

2 2014 绎 Vol.16 No.1 Humans EnglishWeb of Science (acupuncture) AND hypertension(acupuncture) AND blood pressure(acupuncture) AND arterial pressure 淤 RCT 于 淤 Meta 于 Web of Science PubMed (acupuncture) AND hypertension 261 Full text availablerandom 原 ized Controlled TrailClinical TrailHumans English 11 5 [9~13] 3 [9,10,13] 1 [10] [14] 1 [11] 1 [12] Yin C [11] 逸 140 mmhg 逸 90 mmhg 1 Macklin E A [10] Kalish L A [14] 140~179/90~109 mm Hg Flachskampf F A [12] 140~179/ 90~109 mmhg 3 [10,11,13] Macklin E A [10] Flachskampf F A [12] Kalish L A [14] [9] [10,12] [11] 1 1 IF Williams T [9] Physical Therapy ~120 mmhg 4 6 Macklin E A [10] Kalish L A. [14] Hypertension 6.2 Controlled Clinical Trials - 140~179/90~109 mmhg Yin C [11] Neurological Research IF1.5 淤逸 120/80 mmhg 于逸 140/90 mmhg Flachskampf F A [12] Circulation ~179/90~109 mmhg Zhang J [13] Journal of Chiropractic Medicine - 120~165/ 80~110 mmhg

3 绎 2 Williams T [9] 4 15 cm 5min Macklin E A [10] Kalish L A [14] 淤 10~12 2 于 5 Darwin 2 臆 12 6~8 3~5 10 Yin C [11] min 3~ ~4 4 8 Flachskampf F A [12] P1 P2 P min 24 h 24 h Zhang J [13] 2/100 Hz 15 min 30 min [10] 1 [11] Saam 4 淤 于 盂 榆 2 [9,10] [9] [10~12] [13] [11] [9,10,13] [11] 24 h [12] [9,10,12] [11] [13] 4 [9,11~13] 1 [10] RCT CONSORT [15] STRICTA [16] [17] 2000~2006 RCT 1 RCT 5.98% Williams T [9] 3

4 2014 绎 Vol.16 No [18] [19] [20] [21] [22] [10] [23] 2~ min [24] Yin C [11] Eric A [10] [14] 5mmHg Meta [25] 11 RCT Meta [26] RCT 973 RCT Wolf -Maier K, Cooper R S, Banegas J R, et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JA MA, 2003, 289(18) 颐 2363~ Chobanian A V, Bakris G L, Black H R, et al. Seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension, 2003, 42(6) 颐 1206~ Oparil S, Zaman M A, Calhoun D A. Pathogenesis of hypertension. AnnInternMed, 2003, 139(9) 颐 761~ Whitworth J A. World Health Organization (WHO) /International So 原 ciety of Hypertension (ISH) statement on management of hyperten 原 sion. JHypertens, 2003, 21(4) 颐 1983~ Tindle H A, Davis R B, Phillips R S, et al. Trends in use of com 原 plementary and alternative medicine by US adults: Al 原 tern Ther Health Med, 2005, 11(1) 颐 42~49. 6,,,..,2011,31(8) 颐 951~953. 7,,,.., 2007,27(6) 颐 467~470. 8, SCI.,2012,32 (8) 颐 742~ Williams T, Mueller K, Cornwall M W. Effect of Acupuncture - Point Stimulation on Diastolic Blood Pressure in Hypertensive Sub 原 jects: A Preliminary Study. Phys Ther, 1991, 71(7) 颐 523~ Macklin E A, Wayne P M, Kalish L A, et al. Stop Hypertension With the Acupuncture Research Program (SHARP): Results of a Randomized, Controlled Clinical Trial. Hypertension, 2006, 48(5) 颐 838~ Yin C, Seo B, Park H J, et al. Acupuncture, a promising adjunc 原 tive therapy for essential hypertension: a double-blind, randomized, controlled trial. Neurol Res, 2007, 29(Suppl 1) 颐 S98~ Flachskampf F A, Gallasch J, Gefeller O, et al. Randomized Trial of Acupuncture to Lower Blood Pressure. Circulation, 2007, 115 (24) 颐 3121~ Zhang J, Ng D, Sau A. Effects of electrical stimulation of acupunc 原 ture points on blood pressure. JChiroprMed, 2009, 8(1) 颐 9~ Kalish L A, Buczynski B, Connell P, et al. Stop Hypertension with 4

5 绎 the Acupuncture Research Program ( SHARP ) : clinical trial design and screening results. Controlled Clin Trials, 2004, 25(1) 颐 76~ Altman D G, Schulz K, Moher D, et al. The revised CONSORT statement for reporting randomized trials explanation and elabora 原 tion. Ann Intern Med, 2001, 134(8) 颐 663~ Mae Pherson H, White A, Cummings M, et al. Standards for re 原 porting interventions in controlled trials of acupuncture: the STRIC 原 TA recommendations. Acupunct Med, 2002, 20(1) 颐 22~25. 17,,, RCT.,2008,28(6) 颐 439~ ,,,. RCT.,2008() 颐 85~87. 19,,,..,2013,54(5) 颐 369~ ,,,.., 2012,27(12) 颐 3023~ ,,,..,2012,27(11) 颐 2770~ ,,.., 2012,28(4) 颐 42~43. 23,,, , 20(4) 颐 1~4. 24,,,.., 2013,54(1) 颐 8~ Lee H, Kim S Y, Park J, et al. Acupuncture for lowering blood pressure: systematic review and meta -analysis. Am J Hypertens, 2009, 22(1) 颐 122~ ,,. Meta., 2012,18(4) 颐 421~ 423. Reviews on RCT Design Characteristic of Primary Hypertension Treatment with Acupuncture Abroad Zheng Huabin 1, 2, Guo Taipin 2, Shi Jing 3, Zheng Hui 2,LiJuan 2,LiangFanrong 2 (1. Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu , China; 2. College of A cupuncture & Moxibustion and Tui-na, Chengdu University of TCM, Chengdu , China; 3. Y unnan Provincial Hospital of Traditional Chinese Medicine, Kunming , China) Abstract: Primary hypertension is one of the common chronic diseases, as well as the key disease for prevention and treatment by traditional Chinese medicine (TCM). The authors searched and analyzed RCTs studies on primary hyper 鄄 tension treatment with acupuncture in the PubMed. It showed that primary hypertension treatment with acupuncture abroad had high quality methodologies. However, the deficiencies of TCM theories in the treatment plan in these studies were the same as RCTs of acupuncture treatment design of other diseases. It may due to the insufficiency of TCM knowledge and culture differences of researchers aboard. Besides, the small sample amount, various interven 鄄 tions, no blank control, and the using of 24-hour ambulatory blood pressure most of the time, may difficult to objec 鄄 tively evaluate the clinical effect of acupuncture. Therefore, our research team will carry out high quality RCT stud 鄄 ies under the guidance of TCM theories of meridians and syndrome differentiation to further discuss the specificity of acupoints. Keywords: Acupuncture, primary hypertension, RCT, SCI, clinical design 5