Chinese Acupuncture & MoxibustionDec.2011Vol.31No.12 comparedwiththatbeforetreatmentineithergroup (P<0.001P<0.01)butthetemperaturei

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1 DOI: /j Chinese Acupuncture & MoxibustionDec.2011Vol.31No : (2011) :R246.2 : A 檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪 : ( ; ;3. ) [ ] : :59 (31 ) (28 ) (WOMAC) 46m UT-325 : 3 6 WOMAC (P<0.05P<0.01P<0.001); (P<0.05); 6 (P<0.01P<0.05) 6 46m (P<0.01) (P> 0.05) (P>0.05) (49.81±3.10) (40.98±1.67) (P<0.001P<0.01) (P<0.001) : [ ] ; ; Kneeosteoarthritistreatedwithmoxibustion:arandomizedcontroledtrial REN Xiu-mei 12 CAO Jin-jin 2 SHEN Xue-yong 23 WANG Li-zhen 2 ZHAO Ling 2 WU Fan 2 ZHANG Hai-meng 2 (1.Acupuncture-Moxibustion Department Afiliated Hospital of Nantong UniversityNantong Jiangsu ProvinceChina;2.Acupuncture-Moxibustionand Massage ColegeShanghai University of TCMShanghai201203;3.ShanghaiResearchCenterofAcupuncture-Moxibustionand Meridian) ABSTRACT Objective Toobservetheeficacyofmoxibustionontheimprovementinpainstifnessandmotordistur- banceforthepatientswithkneeosteoarthritis (OA)andevaluatetheefectivenessandsafetyofmoxibustiontherapy. Methods Fifty-ninecasesofkneeOA wererandomlydividedintoamoxibustiongroup(31cases)andaplacebomoxibus- tiongroup(28cases)inwhichmoxaconeandplacebomoxastickerwereappliedtoneixiyan(ex-le4)dubi(st35) andashipointsseparately3conesoneachpointineachtreatment.thetreatmentwasgivenonceeverytwodays 3timesperweekcontinuouslyfor6weeks.Thefolow-upvisitwasperformedin6weeksaftertheendoftreatment. The WesternOntarioand McmasterUniversitiesOsteoarthritisIndex(WOMAC)andthetimeof46-meterwalkingatthe fastestspeedwereadoptedtoevaluatetherecoveryofjointfunction.ut-325digitalthermaldetectorwasusedtorecord thetemperaturechangeatthemostapparentpainpointsofkneejointbeforeandaftermoxibustiontreatment.results In moxibustiongroupthescoresin WOMAC werereducedapparentlyin3and6weekstreatmentandduringfolow-upvi- sitseparately(p<0.05p<0.01p<0.001).inplacebomoxibustiongroupduringfolow-upvisitthescoreofstif- nesswaslowerascomparedwiththatbeforetreatment(p<0.05).in6weeksoftreatmentandduringfolow-upvisit thescoresofpainstifnessandmotordisturbanceinmoxibustiongroupwerereducedmuchmoreremarkablyascompared withplacebomoxibustiongroup(p<0.01p<0.05).inmoxibustiongroupaftertreatmentfor6weeksthetimeof46-me- terwalkingatthefastestspeedwasshorterapparentlyascomparedwiththatbeforetreatment(p<0.01)buttherewasno apparentimprovementaftertreatmentinplacebomoxibustiongroup(p>0.05).thediferencewasnotsignificantstatistical- lyingroupcomparison(p>0.05).aftermoxibustionthetemperatureattreatmentpointwas(49.81±3.10) inmoxi- bustiongroupandwas(40.98±1.67) inplacebomoxibustiongroup.thelocalskintemperatureincreasedapparentlyas 973 :2009 CB522901; :S30304; :08 DZ DZ : (1957-) : snowysh@hotmail.com

2 Chinese Acupuncture & MoxibustionDec.2011Vol.31No.12 comparedwiththatbeforetreatmentineithergroup (P<0.001P<0.01)butthetemperatureincreasinginmoxibustion groupwasmuchmoreremarkable(p<0.001).conclusion Moxibustioncanobviouslyimproveintheclinicalsymptomsfor thepatientswithkneeosteoarthritissuchaspainstifnessandmotordisturbance.itisasafeandefectivetherapy. KEY WORDS OsteoarthritisKnee;Moxibustion;RandomizedControledTrial(RCT) [6] [1] ( :ChiECRCT ) Meta [2-5] 65 (33 ) (32 ) 2 3 ; ( P>0.05) 1 1 ( ) ( ) ( x±s) 珚 ( ) ( ) ( x±s ) 珚 ( x±s) 珚 ± ± ± ± ± ± ;3 3 (ACR) ( ) (1995) [7] :11 ;2X ;4 ;3 1.5 ;4 40 ;5 30min; : 6 2 : ~78 ;2 3 : 1 ;3 3 ( ) ;4X : (Kelgren-Lawrencegrade 2); Excel2003 ( ) ;2 ; ( 5 ) ;

2011 12 31 12 Chinese Acupuncture & MoxibustionDec.2011Vol.31No.12 1059 ; 2 2.1 8mm ( 1) [8] 1 2.2 100mm( ) 3 6 14 ; (2) UT-325 ( 3 1 3 618 1 ) 3 2 ; >2 (3)50 (46 m) : 2.

3 Chinese Acupuncture & MoxibustionDec.2011Vol.31No ; mm ( 1) [8] mm( ) ; (2) UT-325 ( ) 3 2 ; >2 (3)50 (46 m) : ( ) =[ 46m - 46m ) 46m ] 100% (1) (Western Ontarioand Mc- Master Universities OsteoarthritisIndexWOMAC): SPSS16.0 ± ( x±s) 珔 WOMAC 46m t P< (1) WOMAC 0( )~ ( 2) 2 WOMAC ( x±s) 珚 ± ± ) 12.67±7.51 3)4) 13.57± )5) ± ± ) 15.39± )5) 14.66± )5) 37.15± ± ) 15.39± )5) 14.97± )5) ± ± ± ± ± ± ± ± ± ± ± ± ) : 1) P<0.05 2) P<0.01 3) P<0.001; 4) P<0.01 5) P<0.05

4 Chinese Acupuncture & MoxibustionDec.2011Vol.31No.12 2 WOMAC (NSAID) [12] ( P>0.05) [13-14] ; WOMAC (P< 0.05P<0.01P<0.001); (P<0.05); 6 (P<0.01P<0.05) (2) ; ( 3) ± ±1.67 2) t P >0.05 <0.001 : 1) P< ) P<0.01; 3) P< m ( s) (%) ± ±4.87 1) 6.68± ± ± ±14.82 t P >0.05 >0.05 >0.05 : 1) P< m WOMAC (P>0.05) ; 46m (t= 3.444P<0.01) (P>0.05) :1 (P>0.05) 2 4 ; 3 ( x±s ) 珚 ± ±3.10 1)3) WOMAC ; 3 ; 3 (P<0.01P<0.001); 6 (P<0.001) (3) 46 m ( 4) m ( x±s) 珚 (OA) 3 [9-10] 53% [11] 4

5 檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪 Chinese Acupuncture & MoxibustionDec.2011Vol.31No [5] BermanB MLaoLLangenbergPetal.Efectiveness ofacupunctureasadjunctivetherapyinosteoarthritis oftheknee:arandomizedcontroledtrial[j].annin- tern Med (12): [6]. [J] (7):388. [7] AmericanColegeofRheumatologySubcommiteeonOs- 46 m teoarthritisguidelines.recommendationsforthe medical 46 m managementofosteoarthritisofthehipandknee[j]. (P>0.05) ArthritisRheum200043(9): [8] ZhaoBWangXLinZetal.Anovelsham moxibus- 10 tiondevice:arandomizedplacebo-controledtrial[j]. 3 1 ComplementTherMed200614(1): [9] DawsonJLinselLZondervanKetal.Impactofper- sistenthiporkneepainonoveralhealthstatusinel- derlypeople:alongitudinalpopulationstudy[j].ar- thritisrheum200553(3): [10] PalmerK TReadingICalnan Metal.Doeskneepainin thecommunitybehavelikearegionalpainsyndrome Pro- spectivecohortstudyofincidenceandpersistence[j].ann Rheum Dis200766(9): [11]. (2007 )[J] (10): [12] Watson MBrookesS TFaulkner Aetal.WITH- [1]. [M]. : DRAWN:Non-aspirinnon-steroidalanti-inflammato- rydrugsfortreatingosteoarthritisoftheknee[j]. 2004:37. [2] CochraneDatabaseSystRev2007(1):CD SangdeeCTeekachunhateanSSananpanich Ketal. [13] TramèrM RMooreR AReynoldsDJetal.Quan- Electroacupunctureversus diclofenacin symptomatic titativeestimationofrareadverseeventswhichfolow treatmentofosteoarthritisoftheknee:arandomized abiologicalprogression:anew modelappliedtochro- controledtrial[j].bmc Complement Altern Med nicnsaiduse[j].pain200085(1-2): :3. [14] [3] SilversteinFEFaichGGoldsteinJLetal.Gastroin- TukmachiEJubbRDempseyEetal.Theefectof testinaltoxicitywithcelecoxibvsnonsteroidalanti-in- acupunctureonthesymptomsofkneeosteoarthritis: flammatorydrugsforosteoarthritisandrheumatoid an open randomised controled study[j].acupunct arthritis:theclassstudy:arandomizedcontroled Med200422(1): [4]. trial.celecoxiblong-term ArthritisSafetyStudy[J]. : [J] (8): JAMA (10): ( : ) : 16 : : :

穨資料題_中三_中五適用__慈禧太后的功過_林麗貞_20

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